Monitor for indications of urinary retention or lowered gastric motility if oliceridine is coadministered with anticholinergics.
iloperidone improves amounts of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Iloperidone can be a time-dependent CYP3A inhibitor and could lead to elevated plasma amounts of drugs predominantly eliminated by CYP3A4.
apalutamide will lessen the extent or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with medicines which are CYP3A4 substrates may end up in lower publicity to these remedies.
Dihydrocodeine can be an opioid analgesic agent used for the management of suffering significant sufficient to have to have an opioid analgesic and for which option remedies are insufficient.
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In addition to their handy outcomes, most medicines can cause check here undesirable side-results Whilst not Absolutely everyone ordeals them. The desk beneath includes the commonest ones connected to diazepam.
These adjustments weren't associated with other abnormal thyroid functionality assessments suggesting hypothyroidism. Irregular thyroid function assessments need to be clinically evaluated.
Energetic metabolites: N-desmethyldiazepam and temazepam, that are both equally further metabolized to oxazepam; mostly eliminated by glucuronidation
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bosentan will minimize the level or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
VALTOCO delivers the same diazepam because the rectal gel trusted by care partners, without the not comfortable delivery.
isoniazid will enhance the amount or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
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butalbital will reduce the level or influence of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.